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The Horn of Life is a healing item in EarthBound. It is rarely dropped by a few enemies, and can be purchased in Saturn Valley or Lost Underworld for $1780. The Horn of Life can cure a character's status conditions and revive a dead or diamondized party member to full HP, just like Healing Ω or a Cup of Lifenoodles. Gone after one use.

Horns of Life are also used in Tenda Village as a form of currency there. One horn will get you a Plain roll, two horns will get you some Plain yogurt, and so on until trading seven horns, which will earn the player a Hall of fame bat. Manly Fish's Brother has a 1/128 chance of dropping one, and since this enemy has a low chance of appearing, this makes the Horn of Life possibly the hardest 1/128 item to get.

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